Liquid-liquid phase separation: Fundamental physical principles, biological implications, and applications in supramolecular materials engineering
December 2023
Liquid-liquid phase separation (LLPS) is a captivating phenomenon in which a uniform mixture spontaneously divides into two liquid phases with differing component concentrations. It is prevalent in...
Anti-aging and anti-inflammatory fulfilled through the delivery of supramolecular bakuchiol in ionic liquid
December 2025
Bakuchiol, as a derivative of retinol, has attracted attention due to its strong anti-aging ability on the skin. However, how to solve its irritability and low permeability is a challenge in the field...
Self-healing hydrogels based on reversible noncovalent and dynamic covalent interactions: A short review
December 2023
The self-healing capability of a material refers to its ability to autonomously heal fractures or defects and restore its original structures and functionalities. Self-healing hydrogels, with enhanced...
Hydrogel with high-order structures: from hierarchical engineering to flexible biomedical applications
December 2026
Hydrogels are promising for flexible biomedical systems, yet their performance is often constrained by conventional composition-dominated networks, which are typically randomly crosslinked and structurally...
Dynamic covalent bond-based materials: From construction to biomedical applications
December 2024
Dynamic covalent bonds (DCBs) have received significant interest due to their unique reversibility and stimuli-responsiveness. The introduction of DCBs provides materials with self-healing and controllable...
Self-assembly of short peptides and DNA-based materials in precision biomedical applications
December 2026
The spontaneous assembly of molecular components into highly organised and functional nanostructures through non-covalent interactions constitutes a defining aspect of advanced biomaterials design....
Supramolecular engineering of luminescent materials: From molecular design to optoelectronic applications
December 2026
Luminescent materials often face trade-offs between efficiency, stability, and dynamic responsiveness, which limit their performance in advanced optoelectronic devices and bioimaging. Supramolecular...
Stimuli-responsive protein hydrogels: From dynamic tuning of hydrogel mechanics to shape morphing
December 2025
Protein hydrogels represent a rapidly evolving class of biomaterials with significant potential in biomedicine, soft robotics, and tissue engineering. These hydrogels are uniquely engineered from natural...
Multifunctional zwitterionic hydrogels: A review of cross-disciplinary applications
December 2026
Owing to their unique molecular structure, zwitterionic hydrogels have emerged as a research hotspot in numerous fields in recent years. Cations and anions are uniformly distributed along the polymer...
Super-hydrated supramolecular hydrogel with persistent minimal friction enabled by zwitterion-driven microphase separation
December 2026
A fundamental challenge for lubricating hydrogels is the inherent trade-off between mechanical robustness and interfacial hydration, necessitating new approaches to achieve both properties. To address...
Zwitterionic hydrogels from material design to wound dressing applications
December 2025
Zwitterionic hydrogels, synthesized from zwitterions such as sulfobetaine, carboxybetaine, and phosphorylcholine, feature a balanced mix of positive and negative charges within the same polymer chains....
Coordination chemistry enabled in vivo radioprotective material for alleviating acute radiation syndrome
December 2026
The most life-threatening injury induced by radiation is acute radiation syndrome (ARS), which is featured by damage to the hematopoietic system and vital organs. However, most efforts focus on scavenging...
Polyrotaxanes in motion: recent advances in slide-ring supramolecular polymers
December 2026
Polyrotaxanes (PRs) are mechanically interlocked supramolecular systems with the ring components threading linear axle component. When two rings are connected with a covalent linker and incorporating...
Light-triggered one-pot synthesis of covalent-supramolecular double network elastomer
December 2026
The double-network (DN) structure is an important strategy for toughening elastomers. Developing efficient preparation methods for DN elastomers remains a key challenge in this field. Herein, we developed...
Supramolecular wearable patch for continuous non-invasive blood glucose monitoring
December 2026
Diabetes is a chronic disease that requires continuous glucose monitoring for effective management, but current monitoring methods exist invasive and non-continuous problems. In this study, we firstly...
Supramolecular self-assembly in solid-state lithium batteries: Bulk electrolyte design and interface engineering
December 2025
The development of solid-state lithium batteries (SSLBs) is pivotal to addressing the escalating global demand for advanced electrochemical energy storage systems, driven notably by electric vehicles...
Perylene diimide supramolecular aggregates: Constructions and sensing applications
December 2023
Perylene diimides (PDIs) with high fluorescence quantum yield and well π-conjugated plane have been widely studied to construct supramolecular aggregates via noncovalent interactions and to further...
Piezoelectric-triboelectric hybrid nanogenerator based on tough, stretchable BaTiO3 doped antibacterial hydrogel for self-powered sensors
December 2025
•A robust and stretchable BaTiO3-doped hydrogel was obtained through arationalpreparation strategy.•The obtainedhydrogel was utilized as electrode material for constructing high-performance piezoelectric-triboelectric...
Biodegradable power sources for transient bioelectronics
December 2025
The development of biodegradable power sources has opened new avenues for transient bioelectronics, offering temporary energy solutions for implantable medical devices. This review presents a systematic...
Tyrosinase inhibitors as melanoma sensitizers: Boosting therapeutic efficacy
December 2025
Melanoma therapy faces critical challenges due to melanin-mediated resistance mechanisms. The use of tyrosinase inhibitors to suppress tyrosinase activity and reduce melanogenesis, thereby sensitizing...
Hydrogen-bonded supramolecular adhesives: Synthesis, responsiveness, and application
December 2023
Adhesive bonding to diverse substances is vital to a great number of the established, cutting-edge and emerging applications. We have witnessed, in the last few years, the transformative progress in...
Fundamental and Application of Co-assembly of Peptides and Proteins: Experiment and Computation
December 2025
Peptides and proteins can co-assemble into various nanostructures based on complementary non-covalent interactions such as electrostatic forces, hydrogen bonding, and hydrophobic associations. These...
Underwater adhesive photonic-ionogels with unchangeable structural color for motion sensing
December 2026
Ionogels have emerged as promising materials for flexible sensors, combining tunable mechanical properties with high ionic conductivity. While integrating colloidal crystals within ionogels can enable...
Interfacial self-assembly of nanoparticles into macroscopic, monolayered films
December 2022
This article offers an overview of recent advances in directing self-assembly of nanoparticles (NPs) at the interfaces between two immiscible fluids, which is aimed at emphasizing that the fluidic interfaces...
Supramolecular fluorescence biosensing based on macrocycles
December 2024
Fluorescence sensing converts chemical events into measurable readings by utilizing fluorescence signals for the qualitative or quantitative detection of specific analytes. Supramolecular chemistry,...
